NCI-Designated Cancer Centers

There are currently 69 NCI-Designated Cancer Centers, located in 35 states and the District of Columbia, that form the backbone of NCI’s programs for studying and controlling cancer. At any given time, hundreds of research studies are under way at the cancer centers, ranging from basic laboratory research to clinical assessments of new treatments. Many of these studies are collaborative and may involve several cancer centers, as well as other partners in industry and the community. Find a center near you and learn about its patient services and research capabilities.

Tracking Treatment Resistance in Metastatic Breast Cancer

New research has shown that treatment-resistant cells shared some common, important functional characteristics—known as their phenotype—explained the study’s senior investigator, Andrea Bild, Ph.D., of the City of Hope Comprehensive Cancer Center in California. In laboratory studies, the research team showed that, guided by the phenotype of the treatment-resistant cells, they could successfully kill those cells with targeted therapies.

Liquid Biopsy: Using Tumor DNA in Blood to Aid Cancer Care

More than 100 years ago, scientists discovered that tumors shed molecules and cells into bodily fluids. Much more recently, researchers have shown that analyzing these molecules and cells can reveal some of the same information that tissue biopsies provide. Liquid biopsy research has recently expanded, generating an entirely new field of study. Both academic and industry researchers from diverse areas of expertise are working on many fronts to develop, refine, and establish clinical uses for liquid biopsy tests.

Vitamin D May Affect Breast Cancer Survival

Researchers analyzed data from nearly 1,700 breast cancer patients in California and found that higher vitamin D levels at diagnosis were associated with better overall survival. This link was strongest in premenopausal women. Researchers found lower vitamin D levels in patients with advanced-stage tumors and the lowest levels in premenopausal women with triple-negative cancer. Triple-negative cancer is the most common type of breast cancer found in women with changes in a gene called BRCA1.

Exercise Good For Cancer Patients During, After Treatment

Exercising during and after cancer treatment is safe and improves quality of life, fitness and physical functioning, new research indicates. Benefits occurred with all types of exercise, said study author Brian Focht. “Overall, resistance exercise, aerobic exercise — and even a combination of aerobic and resistance — resulted in improvement in fitness and quality of life and physical function,” said Focht. He directs the exercise and behavioral medicine lab at the Ohio State University Comprehensive Cancer Center in Columbus.

When Data Doesn’t Tell the Whole Story: Breast Cancer Death Rate Report

Too many women are diagnosed. Too many women die. And women of color fare worse than white women. Whatever the precise gains, we have a long way to go. The ACS reports that, “approximately 252,710 new cases of invasive breast cancer and 63,410 cases of in situ breast carcinoma are expected to be diagnosed among US women in 2017.” Surely we deserve more for all the awareness, the focus on screening, and the billions spent on research.

FDA OKs First At-home Genetic Test for Breast Cancer Risk

The FDA has granted authorization for a direct-to-consumer test for a highly selected group of cancer-associated BRCA mutations. Granted to 23andMe, the authorization covers the Personal Genome Service Genetic Health Risk Report for BRCA1/BRCA2 (selected variants). The test can identify three specific BRCA mutations that occur most often in people of Ashkenazi Jewish descent. The test does not identify any of the other more than 1,000 known BRCA mutations, including mutations found most commonly in the general population.

11 Carcinogens That Are In Your Home

This list of products is only a fraction of the products that you think are safe, but might actually be causing harm to you and your family. The article is not intended to instill fear or apprehension, but to raise awareness and help you make the smartest choices while purchasing or preparing items to be used in your home

Scientists Warn Chemotherapy Treatment May Encourage Aggressive Tumors and Spread Cancer

Mice with breast cancer who were given chemotherapy had double the number of cancer cells in the lungs and bloodstream, compared to mice that did not receive the treatment. Moreover, scientists found that chemotherapy made blood vessels more permeable to cancer cells. Immune cells that transport cancer cells also increased. Chemotherapy has been found to promote cancer spread in humans as well. In twenty patients who received chemotherapy drugs, it was discovered that tumor microenvironments became increasingly favorable for cancer metastasis.

What Are the Types of Radiation Treatment for Breast Cancer?

Although too much radiation was subsequently found to cause cancer, at the right dose its curative properties have been well established. It’s now a common component of treatment for breast cancer, and it can be delivered in a few different ways to either the whole breast or just part of it as external beam radiation or internal radiation.

5 Common Sugar Substitutes That Are Harmful 

While artificial sweeteners have attracted quite a few fans, research has shown that their effects may be very far from positive. Meet the 5 best known artificial sweeteners, some of which we add to our food ourselves and some of them we meet on labels, which can endanger your health and cause much more harm than good …

The ABCs of Food Labels

How do you sort the fact from fiction and get to the bottom of how your food is produced? Fortunately, there are several legitimate certifications that have high standards for animal welfare and environmental practices. These typically ensure compliance through audits and inspections.

Liquid Biopsy: Using Tumor DNA in Blood to Aid Cancer Care

Liquid biopsy research has recently expanded, generating an entirely new field of study. Both academic and industry researchers from diverse areas of expertise are working on many fronts to develop, refine, and establish clinical uses for liquid biopsy tests. Different liquid biopsy tests analyze different kinds of tumor material, such as DNA, RNA, proteins, tiny vesicles called exosomes, and whole cells. The tests detect these molecules or cells in various bodily fluids, including blood, urine, cerebrospinal fluid, or saliva. These body fluids are usually readily accessible, and in most cases the procedure for collecting a sample is less invasive and more easily repeatable than a tissue biopsy.

This feature gives liquid biopsies the potential to be used for several important applications for which tissue biopsies are not well suited, explained Miguel Ossandon, M.S., program manager for the Cancer Diagnosis Program in NCI’s Division of Cancer Treatment and Diagnosis.