Tissue adjacent to tumors may not be “normal,” study finds

Researchers have known that cancer cells interact extensively “with the surrounding microenvironment of the tumor,” added Dinah Singer, Ph.D., director of NCI’s Division of Cancer Biology. “What’s novel here is the suggestion that the interactions extend beyond that to tissue that appears to be pathologically normal.”

Fracking Chemicals Cause Changes to Mammary Tissue 

At levels found in drinking water within a mile of fracking operations, the chemicals used to extract oil and gas disrupt the endocrine systems of mice. Mice were exposed in utero, developing precancerous lesions in breast tissue, decreased sperm counts, and multiple organ impacts after puberty. Meanwhile, in areas of severe drought, some conventional farmers are using “treated” water left over from drilling operations to water their crops.

Are New Cancer Drugs Worth Their Price? 

A new analysis in the BMJ evaluated 48 cancer drugs that the European equivalent of the FDA, the European Medicines Agency, approved before 2009 and 2013 (Davis et al, BMJ, Oct. 4, 2017). The EMA had approved the drugs for 68 different uses, eight on the basis of a single study each. Several studies were not double-blind, considered a standard for drug research. Although it seemed that the medications were extending survival, later research showed that was true only for half of them. In addition, that benefit was judged clinically meaningful only in about half of those cases. The authors concluded that many of these cancer drugs were approved “without evidence of benefit on survival or quality of life.” Even more than three years after approval there remains a paucity of solid scientific evidence of substantial benefit.

Breast Cancer Survivor Story Hard Life After Treatment

Complaining is always awkward, but complaining about cancer gets you more side-eye than a priest at a pro-choice rally. People prefer to hear about drama they can help with, like decoding texts from a toxic ex. Scary diseases should be avoided in polite conversation, because, well, we’d all like to avoid them, but this goes doubly if you’re a cancer survivor: You’ve survived, after all.

Share the Love on Valentine’s Day, Not GMOs

Most of America’s favorite Valentine’s Day sweets are chockfull of ingredients that are highly likely to be genetically engineered– such as sugar, soy lecithin, corn starch, and corn syrup and partially hydrogenated soybean oil. GMOs have never been proven safe for consumption. GMOs are designed to work hand-in-hand with pesticides, and a growing body of studies expose the health effects of exposure to and consumption of these toxic chemicals.

Cribriform breast cancer: Grading and types

Cribriform breast cancer is a rare form of breast cancer that is often combined with another form of breast cancer. It is typically a low-grade and slow-growing cancer with a better outlook than most other types of invasive breast cancer.

Calif. Governor Signs Cleaning Product Disclosure Law 

The Cleaning Product Right to Know Act of 2017 – Senate Bill 258, authored by Sen. Ricardo Lara, D-Bell Gardens – requires the ingredients in cleaning products to be listed on both product labels and online. This applies particularly to chemicals whose ability to harm human health or the environment has been recognized by established scientific authoritative bodies. Under this law, the mandatory disclosure also applies to ingredients in fragrance mixtures, which have been tightly held secrets until now.

Why These Women Said ‘No’ to Breast Reconstruction After Mastectomy

“Reconstruction is a voluntary and deeply personal choice,” says Melissa L. Pilewskie, MD, a surgical breast oncologist at Memorial Sloan Kettering Cancer Center in New York City. While some women will undergo the surgery, others want a more minimal approach, she says. “They just want to get through treatment and not add anything else, or it’s simply not important to them.”

New Method That Targets Breast Cancer Metastasis in Bones Developed

A new method using small particles loaded with chemotherapy drugs is a viable approach to target breast cancer cells that have spread to the bones, according to a report that appeared in the journal Cancer Research. The strategy, developed by a research team at Washington University School of Medicine in St. Louis, Missouri, combines a nanoparticle-based drug delivery method with a surface molecule called integrin β3. The integrin enables the small particles to get inside the bones and deliver the chemotherapy drug directly to the cancer cells.

Weight loss surgery reduces cancer risk by 33 percent in women

“We found,” says lead researcher Dr. Daniel Schauer, “[that] having bariatric surgery is associated with a reduced risk of cancer, especially obesity-associate[d] cancers including postmenopausal breast cancer, endometrial cancer, pancreatic cancer, and colon cancer. What’s surprising is how great the risk of cancer was reduced.”

Breast cancer: Bacterial deficiency linked with onset

“In our wildest dreams,” says Dr. Eng, “we hope we can use microbiomics right before breast cancer forms and then prevent cancer with probiotics or antibiotics.” “If we can target specific pro-cancer bacteria,” adds Dr. Grobmyer, “we may be able to make the environment less hospitable to cancer and enhance existing treatments.”