In a lumpectomy, an oncologist operates on the affected breast and removes both the cancerous tumor plus tissue surrounding the tumor. He or she tries to spare as much of the breast as possible, only removing whatever is necessary. According to BreastCancer.org, a lumpectomy is considered to be a breast preservation surgery in hopes to doing minimal change to your body. Sometimes, it is called a partial mastectomy.
Vitamin C is up to ten times more effective at stopping cancer cell growth than pharmaceuticals such as 2-DG, according to scientists in Salford, UK. The research, published in Oncotarget, is the first evidence that Vitamin C (ascorbic acid) can be used to target and kill cancer stem cells (CSCs), the cells responsible for fuelling fatal tumours.
Rather than saving lives, drug companies are concerned mainly with creating expensive, patentable drugs that treat chronic conditions like high blood pressure, diabetes, and heartburn. This is partly because the cost of gaining FDA approval is so high due to the need to conduct randomized controlled trials to prove a drug is “effective.” If a substance isn’t patentable, the cost of getting FDA approval is prohibitive. This dynamic is also what keeps other natural treatments from gaining FDA approval.
Women with the highest cholesterol levels had the lowest risk of breast cancer. In fact, the number was 30% lower. The same study found women had a 39% lower risk of melanoma and a 39% lower risk of lymphoma/leukemia when their cholesterol levels were the highest.
More than half of older early-stage breast cancer patients received more radiation therapy than they needed, resulting in unnecessary treatments, more risk of secondary cancers, and tens of millions of dollars in extra healthcare costs. While evidence from other studies proves that treatment with a four-week course of breast radiation costing $8,000 is just as effective as the standard, six-week regimen, which costs over $13,000, the new study found that 57 percent of women who qualified for shorter radiation therapy regimens — or who could have foregone radiation treatment entirely — still received the longer, more expensive treatment.
Breast cancer patients who smoke have a much higher risk of developing lung cancer or having a heart attack than those who don’t smoke or who quit before radiotherapy, according to a study. The risk that non-smokers who receive radiotherapy will die of lung cancer or a heart attack is only 0.6%. It increases to 5% in long-term smokers, however, the research showed. The findings suggest that the risk of radiotherapy for long-term smokers may outweigh the benefit of lower breast cancer mortality. But if patients stop smoking before radiotherapy, they can substantially reduce their risk, the researchers said.
The proteins eIF4E and eIF5 are involved in male breast cancer (MBC), and are biomarkers of a poorer disease prognosis, according to researchers at the University of Leeds in England. Patients with higher eIF4E and eIF5 levels were 2.66 times more likely to die of the disease than patients with lower levels. Treating an MBC patient with a combination of dactolisib, a PI3K inhibitor, and Afinitor (everolimus), which is an mTOR inhibitor, reduced the expression of eIF4E and eIF5 in tumor samples. The results of the study suggest that simple tests to assess eIF4E and eIF5 levels could help doctors adjust treatments and improve outcomes for MBC patients.
A review of differences in cancer survival rates found that after consideration of stage at diagnosis, socioeconomic status, and treatment, black Americans had about 25% increased mortality rates for most types of cancer [Grant, 2012]. The difference was consistent with the fact that black Americans have 25-hydroxyvitamin D concentrations about 40% lower than white Americans since their dark skin reduces the production rate of vitamin D in the sun. A paper from the Roswell Park Cancer Center concluded “The relationship of vitamin D with breast cancer risk may be subtype-specific, with emerging evidence of stronger effects of vitamin D for more aggressive breast cancer, particularly in women of African ancestry.” [Yao, 2013].
The majority of breast cancers are estrogen-receptor positive and often treated with anti-estrogen drugs such as tamoxifen. However, resistance to the hormone therapy eventually develops in a large number of patients, leaving them with few options. Now, new research reveals a molecular explanation for this type of drug resistance and could lead to new therapies and better treatment decisions for estrogen-driven breast tumors.
Using human heart cells generated from adult stem cells, researchers have developed an index that may be used to determine how toxic a group of cancer drugs, called tyrosine kinase inhibitors (TKIs), are to human cells. While 26 TKIs are currently used to treat a variety of cancers, some can severely damage patients’ hearts, causing problems such as an irregular heartbeat or heart failure.
Ibrance (palbociclib) was granted full FDA approval for use in combination with letrozole (Femara) in the frontline setting of patients with postmenopausal women who have ER-positive, HER2-negative metastatic breast cancer.
If you or someone you love has just been diagnosed with breast cancer, your mind is probably spinning. Here, breast cancer columnist, Nancy Brier, shares seven things she learned from her experience that everyone should know:
The risks that GMOs pose are very real and affect us even when we don’t directly consume them. The pesticide-laden farming practices that GMO seeds enable further poison our air and water. GMO seeds are more than a farming practice; they are shaping our entire way of life. Understanding these risks can help us to be better stewards — even activists — for our land, air, and bodies, helping to create a cleaner world where seeds are simply seeds and cancer isn’t a household term.
Whether you can work during cancer treatment depends on: the type of treatment you are getting, the stage of your cancer, your overall health, and the kind of work you do
Many of us are at a place of being completely overwhelmed even before a breast cancer diagnosis further disrupts our lives. It is not enough that we are working full time to support our families, juggling kid’s commitments, homework, household chores, and keeping the bills paid on time, not to mention the mounds of laundry. There is little time to care for ourselves until that call comes and taking care of ourselves becomes one more thing we MUST do. We feel like everything has been thrown at us, including the proverbial kitchen sink, where we see ourselves spinning out of control and going down the drain, never to emerge financially. As treatment begins, the medical bills begin to pile up, often remaining unopened as it is just too painful to look at the cost of care to save our lives.
FDA Approves CDK4/6 Inhibitor, Kisqali, to Treat Type of Metastatic Breast Cancer – Breast Cancer News
The U.S. Food and Drug Administration has approved Kisqali (ribociclib), in combination with an aromatase inhibitor as first-line treatment for post-menopausal and hormone-positive, HER2-negative metastatic breast cancer patients.
Breast cancer patients in the U.K. are being given bamboo bras to help them recover from breast cancer surgery. According to a report in the Express, the National Health Service is giving the bras to women following their breast cancer surgery because they have been proven to help prevent post-surgery infections. The bras also provide women with extra support and comfort which regular bras can’t do. The soft fiber from the bamboo plant was found to have antibacterial properties in clinical trials which could help the 10 percent of women who get infections following mastectomies in the U.K.
Women with the highest vitamin D levels were 28 percent less likely to die of any cause during the study than women with the lowest vitamin D levels, after accounting for tumor characteristics and other factors, the researchers report in JAMA Oncology.
UK-based researchers noted that the plant — sometimes known as Virgon’s Mantlem — has long been used in rural Pakistan to help women with breast cancer. The lab based findings suggest the Fagonia cretica plant, found in arid, desert regions of Pakistan, India, Africa and parts of Europe, contains potential anti-cancer agents acting either independently or in combination against breast cancer cell proliferation.
Using nanoparticles to deliver an experimental drug directly into triple-negative breast cancer cells could be an effective way to fight this very aggressive cancer, which has very few treatment options. The drug is a peptide that is unstable, and delivering it directly into cells means that it can reach its target before degrading.